Basic Information
VIS ID
TVIS10010302
Fusion event
HBV-LOC107987338 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1773
Orient
-
Integrated sequence
TCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGT| |ACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCT
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
7366598/7498557 (Hg38)
End
7366598/7498557 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107987338
Nearest miRNA
hsa-mir-3690-2/Upstream/2892329; hsa-mir-12120/Downstream/5980620;
Nearest TSS
ENST00000430575/Upstream/587871; ENST00000413466/Downstream/202690;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/223374, chrY-CpG: 20/Downstream/61581
Nearby gene
PRKY(-117010) ; TTTY16(+200800) ;
Upstream sequence
ttagggttagggtagggttagggttagggttaggggttaggggttagggtagggttagggtgagggtgagggtgagggtgagggtgagggtgagggttag
Downstream sequence
atatgcaatttacccacgtaacaaacttgcacgtggacattctgagcctaaaataaaagttggaaagaaaaaaGAAGAGAAGGAAAATGGAATAACACGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate