Basic Information
VIS ID
TVIS10010303
Fusion event
HBV-LOC107987338 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
7366772/7498731 (Hg38)
End
7366772/7498731 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107987338
Nearest miRNA
hsa-mir-3690-2/Upstream/2892503; hsa-mir-12120/Downstream/5980446;
Nearest TSS
ENST00000430575/Upstream/588045; ENST00000413466/Downstream/202516;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/223548, chrY-CpG: 20/Downstream/61407
Nearby gene
PRKY(-117184) ; TTTY16(+200626) ;
Upstream sequence
gttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtga
Downstream sequence
TGAAGCCCTAGAGAAGCTCACTAGAGTGGAAATGGCTGTGTATTGATGGGGTCCTTAAGTGATCATGGGAGTGATTGATGCCCACCTGGACTCAAGAATC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate