CD1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010306
Fusion event
HBV-CD1B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2132
Orient
+
Integrated sequence
CTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGA| |AGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTT
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
158269671/158299881 (Hg38)
End
158269671/158299881 (Hg38)
Orient
+
Location type
Intronic
Target gene
CD1B
Nearest miRNA
hsa-mir-101-1/Upstream/1363637; hsa-mir-1182/Downstream/1600098;
Nearest TSS
ENST00000473358/Upstream/8611; ENST00000464822/Downstream/31144;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/118168, chr1-CpG: 44/Downstream/871531
Nearby gene
CD1C(-5107) ; CD1B(+28069) ;
Upstream sequence
ttatattatcctctgatggtagtttgtatttttgtgggatcagtggtgatatcccctttatcattttttattgtgtctatatgattcttctctcttttct
Downstream sequence
tctttattagtcttgctagtggtctatcaattttgctgatcttttcaaaaagccaggtcctggattcattgatcttttgaagattttttttgtgtcttta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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