VISDB Viral Integration Site DataBase

VIS ID

TVIS10010307

Fusion event

HBV-MARK1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

344

Orient

-

Integrated sequence

AGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAAC| |CTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTT

Chromosome

chr1

Cytoband

q41

Reference genome

Start

End

220818842/220645500 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-1283

Nearest miRNA

hsa-mir-101-1/Upstream/444881; hsa-mir-1182/Downstream/3611540;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/116494, chr1-CpG: 85/Downstream/44665

Upstream sequence

cttaaattgaggcagtaataaatcgcctaccaaccaaaaatagcccaggaccagatggatttacagctgaattctaatagaggtacaaagaggagctgaa

Downstream sequence

accatttcttctgaaactattccaaacaattgaaaaggagggactcctccctgactcattctgtgaggccaacatcatcctgataccaaaatctagcaga