Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010308
Fusion event
HBV-OR2L13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2720
Orient
+
Integrated sequence
AGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAG| |TTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTC
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
End
248194670/248031368 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/829308; hsa-mir-3124/Downstream/795009;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/93944, chr1-CpG: 49/Downstream/660361
Upstream sequence
GAATTAGAGCCTTGGAACATGAATAATCAAAGAGATGCTACATTGGTGTTCATGAGATATtgtaacatcgcagaacacatctcctgcccctcagcacttg
Downstream sequence
taaagtcctgttaacaagagcaaggtctggtagaaagaaagactttttcttccaagcttagctgaggggaagcaggacaggcttctgccttaatgggcag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.