CPT2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010310
Fusion event
HBV-CPT2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
26
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCT| |GCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATC
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
53677670/53211998 (Hg38)
End
53677670/53211998 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
CPT2
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-378a-3p
Nearest miRNA
hsa-mir-12136/Upstream/1375596; hsa-mir-101-1/Downstream/842081;
Nearest TSS
ENST00000473358/Upstream/4523; ENST00000569869/Downstream/1474;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14855, chr1-CpG: 44/Downstream/8226
Upstream sequence
tttttttttttggagacacggtctcattctgtcacccaggctggagtacagtggtgcaatcatggctcactgcaacctcaacttccttggctcaaacaat
Downstream sequence
cctcctgcctcagcctcccaaatagctgggactataggcatgcaccaccatgcccagctgatattttaatttttttttttttttgagatggactcttgct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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