Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010321
Fusion event
HBV-PRKCQ integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2132
Orient
+
Integrated sequence
CTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGA| |AGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTT
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
Start
End
6493159/6451197 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-3155a/Upstream/298920; hsa-mir-107/Downstream/5679563;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/230289, chr10-CpG: 77/Downstream/128748
Upstream sequence
gagacacaaaaaacccttcaaaaaattaatgaatccaggagctggttttttgaaaggatcaacaaaattgatagaccgctagcaagactaataaagaaaa
Downstream sequence
aaagagagaagaatcatataaacacaataaaaaatgataaaggggatatcaccactgatcccacagaaatacaaactaccatcagagaatactacaaaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.