Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010322
Fusion event
HBV-FAM149B1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
26
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCT| |GCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATC
Host Sequence
Chromosome
chr10
Cytoband
q22.2
Reference genome
Start
End
74959369/73199611 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1265/Upstream/478511; hsa-mir-107/Downstream/2352847;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/31461, chr10-CpG: 68/Downstream/47260
Upstream sequence
tggccAATAACTGTTATTCTTTTTATTTGGTTGtttgttttaggagacagggtctcactatgttgcccaggctgtcctcaaactcctgagctcaagagat
Downstream sequence
cctcctgcctcagcctcccaaatagctgggactataggcacatgccactgtacccagcCTATTCCTTTGTTAAATAAATGAATTACAGACATTATATAAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.