VISDB Viral Integration Site DataBase

VIS ID

TVIS10010330

Fusion event

HBV-NARS2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1606

Orient

-

Integrated sequence

CGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGT| |CGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCAT

Chromosome

chr11

Cytoband

q14.1

Reference genome

Start

End

78150340/78439294 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-let-7b-5p

Nearest miRNA

hsa-mir-10392/Upstream/3104108; hsa-let-7a-2/Downstream/962728;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/20940, chr11-CpG: 53/Downstream/135066

Upstream sequence

gctgggctaatgtttgttatttttggtagagatggggttttaccatgttggtcaggctggtctcgaactcctgacctcaagtgatccacctgccttggcc

Downstream sequence

tcccaaagtgctgggattacagccgtgagccaccgcacccACGGTGGCTTTGGCTTTTTTTTAAGGCTAGTGGTTTAGCTTTTTTTAAGGCTAGTTTTTA