Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010341
Fusion event
HBV-C12orf71 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
753
Orient
-
Integrated sequence
CTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGG| |TATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAA
Host Sequence
Chromosome
chr12
Cytoband
p11.23
Reference genome
Start
End
27236694/27083761 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/1209682; hsa-let-7i/Downstream/15239939;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/60851, chr12-CpG: 67/Downstream/160288
Upstream sequence
ATGGTTACTCTGCAATTTTTAACCACTTCTTATTAATGCtaaataaatctgtaataaacccgcttttccataaatctttgactatgtctcttatttttct
Downstream sequence
atatgtaggattaatggaccaaaccccataaatatattaaagtcttgtggtagttgataccaaattactttccagaaggttTTGGTATTTAGATGCCCAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.