VISDB Viral Integration Site DataBase

VIS ID

TVIS10010349

Fusion event

HBV-CPNE8 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1819

Orient

+

Integrated sequence

TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA

Chromosome

chr12

Cytoband

q12

Reference genome

Start

End

39236639/38842837 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-8485 ; hsa-mir-4719

Nearest miRNA

hsa-mir-1244-3/Upstream/12968758; hsa-let-7i/Downstream/3480863;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/525996, chr12-CpG: 29/Downstream/62609

Upstream sequence

tggctaatttttgtatttttagtagagacggggtttcaccatgttggccaggctggtctcgaactactaacctcaagtaatccgcccccctcagcctcca

Downstream sequence

aaaagtgctgggattacaggcgtgagccaccgtgcctagccTAAAATTACCATCTTTCTTTTAACACAATTTTTCTTCTAACTTTTCTAAATATATCAAG