Basic Information
VIS ID
TVIS10010355
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2876
Orient
+
Integrated sequence
TTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAAT| |CCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAG
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
End
55986209/55592425 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/1255111; hsa-let-7i/Downstream/1602079;
Nearby gene
OR2AP1(-17081) ; OR10P1(+44467) ;
Upstream sequence
ccaacatattaataatgggagactttaacaccccacagtcaacattagacagatcaacgagacagaaagtcaacaaggatacccaggaattgaactcagc
Downstream sequence
tctgcaccaagcagacataatagacatctacagaactctccaccccaaatcaacagaatatacattttattcagcaccacaccacacctattccaaaatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate