CD163L1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010359
Fusion event
HBV-CD163L1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2132
Orient
+
Integrated sequence
CTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGA| |AGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTT
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
7576194/7423598 (Hg38)
End
7576194/7423598 (Hg38)
Orient
-
Location type
Intronic
Target gene
CD163L1
miRNAs that regulate target gene
hsa-mir-590-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-141/Upstream/459407; hsa-let-7i/Downstream/1815869;
Nearest TSS
ENST00000382841/Upstream/19718; ENST00000345088/Downstream/20548;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/233396, chr12-CpG: 70/Downstream/16212
Upstream sequence
agagacagaaaaaaaccttcaaaaaaacaatcaacccaggagctggttttttgaaaagattaacaatatagataaaccactagccagactaataagaaag
Downstream sequence
aaaagagagaagaatcatatagacacaataaaaaatgataaaggggatatcaccactgatcccacagaaatacaaactaccgtcagagaacactatatcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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