Basic Information
VIS ID
TVIS10010365
Fusion event
HBV-chr13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1639
Orient
-
Integrated sequence
ACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATA| |TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
37648094/37073957 (Hg38)
End
37648094/37073957 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/12911453; hsa-mir-1267/Downstream/2590077;
Nearest TSS
ENST00000623511/Upstream/14244; ENST00000612438/Downstream/31707;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/14128, chr13-CpG: 45/Downstream/795588
Nearby gene
SUPT20H(-14244) ; CSNK1A1L(+29303) ;
Upstream sequence
acctggctaatttttgtatttttagtagagatggggttttgccatgttggccaggctggtctcgaactcctgacctcaagtgatccacctgccttggcat
Downstream sequence
cccaacatgctgggattacaggcgtgagccactgcgcccagccCCCGCTTCTTTTGTTAAGATggatttgaaaaatcttgctctcctgccttcttgcttt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate