VISDB Viral Integration Site DataBase

VIS ID

TVIS10010392

Fusion event

HBV-AATF integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2713

Orient

+

Integrated sequence

TGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAA| |CATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTT

Chromosome

chr17

Cytoband

q12

Reference genome

Start

End

35340571/36983272 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-151a-3p ; hsa-mir-149-5p ; hsa-let-7b-5p ; hsa-mir-4530 ; hsa-mir-1226-3p ; hsa-mir-634 ; hsa-mir-525-3p ; hsa-mir-524-3p

Nearest miRNA

hsa-mir-1180/Upstream/4633070; hsa-mir-10226/Downstream/50473;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/33815, chr17-CpG: 76/Downstream/375581

Upstream sequence

ctaggactactggtgtacgctgccatacctggctaatttttgtatttttttgtagagacagggtcttcctacattgtccgggctggtcttgaactcctgg

Downstream sequence

tctcaagcagtttatccacctcagcctcccagagtgctgtgattacaggtgtgagccaccacatcaggccTTAGtttttttgtttttgtttttgagatgg