Basic Information
VIS ID
TVIS10010400
Fusion event
HBV-chr18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2588
Orient
+
Integrated sequence
GGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAAC| |AGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAA
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
78016181/80258298 (Hg38)
End
78016181/80258298 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/7404916;
Nearest TSS
ENST00000575820/Upstream/10752;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/10510, None/Downstream
Nearby gene
PARD6G(-10784) ;
Upstream sequence
aagatctatatctggtataactattcttgttttatattttattggagtggaacagctcatgtcctcggtctcttgcctcggcaAAGATTAGAttagggtt
Downstream sequence
aggtgagggtgagggtgagggtgagggtgagggtgagggtgagggttagggttagggtgagggtgagggtgagggtgagggtgagggtgagggtgagggt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate