Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010408
Fusion event
HBV-CCDC148 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2876
Orient
+
Integrated sequence
TTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAAT| |CCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAG
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
End
159277733/158421221 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-128-1/Upstream/7052810; hsa-mir-10b/Downstream/765614;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/544388, chr2-CpG: 169/Downstream/35439
Upstream sequence
cccacacaataataatgggagactttaacaccccactgtcaacatcagacagatcaacgagacagaaagttaacaaggatatccaggaattgaactcagc
Downstream sequence
tctgcaccaagcagacataatagacatctacagaactctccaccccaaatcaacagaatacacattcttctcagcaccacatcacacttattccaaaatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.