Basic Information
VIS ID
TVIS10010420
Fusion event
HBV-LINC01643 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1639
Orient
-
Integrated sequence
ACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATA| |TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
34438884/34042895 (Hg38)
End
34438884/34042895 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC01643
Nearest miRNA
hsa-mir-1286/Upstream/606226; hsa-let-7a-3/Downstream/1292745;
Nearest TSS
ENST00000624155/Upstream/25422; ENST00000624442/Downstream/166367;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/120246, chr22-CpG: 76/Downstream/1214473
Nearby gene
LARGE1(-122468) ; ISX(+1023246) ;
Upstream sequence
TTCCCATCATGACTGACCGTCAGATATAAAACCGTTTTGAAAACATAACATCTTGAGTGgggtgtggtggttcatgcctgtaatcccagcactttgggtt
Downstream sequence
gccaaggcaggtggatcacttgaggtcaggagttcgagaccagcctggccaacacggtgatactccgtttctactaaaaatacaaaaattagccatgtgt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate