Basic Information
VIS ID
TVIS10010469
Fusion event
HBV-LINC01470 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
339
Orient
-
Integrated sequence
ACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCA| |CCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGT
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
152135092/152755532 (Hg38)
End
152135092/152755532 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC01470
Nearest miRNA
hsa-mir-10397/Upstream/1233384; hsa-mir-103a-1/Downstream/1591574;
Nearest TSS
ENST00000502646/Upstream/66003; ENST00000520353/Downstream/216251;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/830269, chr5-CpG: 50/Downstream/1283091
Nearby gene
NMUR2(-350252) ; GRIA1(+734992) ;
Upstream sequence
cctcagccttctgagtagcttggattacaggcgcccgctaccacgcctggctaatttttgtattttttagtagagacggggtttcatcatgttggccagg
Downstream sequence
accatttcttctgaaactattccaaacaatagaaaaagagggactcttccctaactcattttatgagtccagcatcatcctgatatcaaaacctggcaga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate