VISDB Viral Integration Site DataBase

VIS ID

TVIS10010484

Fusion event

HBV-CASTOR2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

26

Orient

+

Integrated sequence

AATTCCACAACCTTCCACCAAACTCT| |GCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATC

Chromosome

chr7

Cytoband

q11.23

Reference genome

Start

End

74403506/74989361 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-676-5p ; hsa-mir-3065-5p ; hsa-mir-7160-3p ; hsa-mir-100-3p ; hsa-mir-4642 ; hsa-mir-5093 ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-580-5p ; hsa-mir-191-5p ; hsa-mir-1271-5p ; hsa-mir-96-5p ; hsa-mir-182-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4755-3p ; hsa-mir-1233-3p ; hsa-mir-1236-3p ; hsa-mir-877-3p ; hsa-mir-4258 ; hsa-mir-6840-5p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-4687-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-214-5p ; hsa-mir-766-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-3613-3p ; hsa-mir-4523 ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-1303 ; hsa-mir-6866-5p ; hsa-mir-877-5p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-7158-5p ; hsa-mir-4680-5p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-6873-5p ; hsa-mir-3692-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-3976 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-1180-3p ; hsa-mir-1249-5p ; hsa-mir-125a-3p ; hsa-mir-1275 ; hsa-mir-138-5p ; hsa-mir-2117 ; hsa-mir-28-5p ; hsa-mir-296-3p ; hsa-mir-3139 ; hsa-mir-3191-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-3907 ; hsa-mir-4270 ; hsa-mir-431-3p ; hsa-mir-4441 ; hsa-mir-4443 ; hsa-mir-4447 ; hsa-mir-4458 ; hsa-mir-4472 ; hsa-mir-4487 ; hsa-mir-4497 ; hsa-mir-4500 ; hsa-mir-4525 ; hsa-mir-4537 ; hsa-mir-4664-3p ; hsa-mir-4665-5p ; hsa-mir-4685-5p ; hsa-mir-4710 ; hsa-mir-4723-5p ; hsa-mir-5010-5p ; hsa-mir-518c-5p ; hsa-mir-548q ; hsa-mir-5584-5p ; hsa-mir-5698 ; hsa-mir-6077 ; hsa-mir-625-5p ; hsa-mir-6515-5p ; hsa-mir-6730-5p ; hsa-mir-6731-5p ; hsa-mir-6732-5p ; hsa-mir-6754-5p ; hsa-mir-6760-5p ; hsa-mir-6764-3p ; hsa-mir-6784-5p ; hsa-mir-6797-5p ; hsa-mir-6799-5p ; hsa-mir-6804-5p ; hsa-mir-6824-3p ; hsa-mir-6825-5p ; hsa-mir-6837-5p ; hsa-mir-6870-5p ; hsa-mir-708-5p ; hsa-mir-7111-5p ; hsa-mir-7113-5p ; hsa-mir-8085 ; hsa-mir-9500 ; hsa-mir-98-5p ; hsa-mir-1827 ; hsa-mir-204-3p ; hsa-mir-2467-3p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-377-5p ; hsa-mir-3929 ; hsa-mir-4257 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4646-5p ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-4747-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-490-3p ; hsa-mir-5196-5p ; hsa-mir-6086 ; hsa-mir-6500-3p ; hsa-mir-665 ; hsa-mir-6808-5p ; hsa-mir-6828-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-7851-3p ; hsa-mir-940

Nearest miRNA

hsa-mir-10525/Upstream/393335; hsa-mir-10399/Downstream/925836;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/23807, chr7-CpG: 55/Downstream/84156

Upstream sequence

tggtcttgaactcctggcatcaagtgatctgcctgtcttggcctcccaaagtgctgggatcccagCctctctctctctctttctcactctctctctctcc

Downstream sequence

tcctcctgcctcagcctcccaaatagctgggactacaggagcatgccaccatgcctgggtaatttttgttttgtttttgagatggagtctcgctctgtca