Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010486
Fusion event
HBV-ZNF804B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2917
Orient
+
Integrated sequence
GTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTT| |CAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTC
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
Start
End
88909205/89279891 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/13364622; hsa-mir-10399/Downstream/2924124;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/519922, chr7-CpG: 98/Downstream/838687
Upstream sequence
TGAGTCAgaggccattttaaacagcgaaatcaccaagaaaaagcacaagaatgtgaaaaacatggcactaattaaatagactgcaaagtggataccagtt
Downstream sequence
tctgcaccaagcagacctaatagacatctacagaactctccaccccaaatcaacagaatatacatttttttcaacaccacaccacacctattccaaaatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.