VISDB Viral Integration Site DataBase

VIS ID

TVIS10010493

Fusion event

HBV-CCDC171 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1639

Orient

-

Integrated sequence

ACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATA| |TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG

Chromosome

chr9

Cytoband

p22.3

Reference genome

Start

End

15835680/15835682 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6832-3p ; hsa-mir-4753-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-130b-5p ; hsa-mir-4282 ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-500a-3p ; hsa-mir-642a-5p ; hsa-mir-6804-3p ; hsa-mir-600 ; hsa-mir-3130-3p ; hsa-mir-4469 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-1306-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-875-5p

Nearest miRNA

hsa-mir-101-2/Upstream/9827778; hsa-let-7a-1/Downstream/2737624;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/282346, chr9-CpG: 30/Downstream/891179

Upstream sequence

TCCCTTCTTCCCTCGCCTTTCTCCCCTGTCCTCTGCGTGTTTGTCATCCCACCCTGCTCCTTTCTCCCTAATTTCAATCTCTGTTCTAAAATGGTTTGAC

Downstream sequence

tcccaaggtgctgggattacaggcatgagccactgcgcctggcTGTCAGTTGCATTTTTAATTACATAAAGTTTATACATATTATATTGAAAGTAATAAA