VISDB Viral Integration Site DataBase

VIS ID

TVIS10010513

Fusion event

HBV-SLC16A4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

752

Orient

-

Integrated sequence

CCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTG| |GTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAA

Chromosome

chr1

Cytoband

p13.3

Reference genome

Start

End

110929720/110387098 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-125b-5p ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-623 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6780b-3p ; hsa-mir-4780 ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-890 ; hsa-mir-7977 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-661 ; hsa-mir-4252 ; hsa-mir-4486 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-1276 ; hsa-mir-20b-3p

Nearest miRNA

hsa-mir-101-1/Upstream/788131; hsa-mir-11399/Downstream/2074672;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/46920, chr1-CpG: 67/Downstream/20172

Upstream sequence

ATCACATCCCTGCTTAATTTTTCTCATTAGCTTCTCATAGCCTCAAGAGCCATTCTCATCTCTTCAGTTTCATCAACTATCCCCTTCATCCTTATTTGTT

Downstream sequence

TATTCATAAATGTGTGCAGCTatcaattcatccatccatctatccatccaccaacagtattttactgagtgcctactatgttccaggctgtatactggca