Basic Information
VIS ID
TVIS10010517
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2904
Orient
-
Integrated sequence
CCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGT| |TGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATT
Host Sequence
Chromosome
chr1
Cytoband
p11.1
Reference genome
End
121484897/121743099 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/4648371; hsa-mir-1182/Downstream/24107488;
Nearby gene
EMBP1(-171211) ;
Upstream sequence
gaacgttcccttagacagagcagatttgaaacactctatttgtgcaatttgcaagtgtagatttcaagcgctttaaggtcaatggcagaaaaggaaatat
Downstream sequence
cttcgtttcaaaactagacagaatcattcccacaaactgcgttgtgatgtgtttgttcaactcacagagtttaacctttctgttcatagagcagttagga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate