VISDB Viral Integration Site DataBase

VIS ID

TVIS10010518

Fusion event

HBV-RERE integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1064

Orient

-

Integrated sequence

TAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTG| |TATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAAC

Chromosome

chr1

Cytoband

p36.23

Reference genome

Start

End

143292662/8797684 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-200b-3p ; hsa-mir-429 ; hsa-mir-92b-3p ; hsa-mir-301a-3p ; hsa-mir-320a ; hsa-mir-4681 ; hsa-mir-4722-3p ; hsa-mir-4763-5p ; hsa-mir-4769-3p ; hsa-mir-596 ; hsa-mir-6501-3p ; hsa-mir-6727-3p ; hsa-mir-6817-5p

Nearest miRNA

hsa-mir-12136/Upstream/2367788; hsa-mir-101-1/Downstream/68818;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/94163, chr1-CpG: 100/Downstream/19269

Nearby gene

ANKRD20A12P(-579057) ; LOC100130000(+394468) ;

Nearest cancer related gene

RERE(OG, No orient, 0)

Upstream sequence

cctcatataggattccagaacacttctgctgtggtctgaatgtttgttcctcacataggattccagaatactcctgccatggtctgaatgtttgtccctc

Downstream sequence

acataggattccagaacattcatgctggggtctcaatatttcccttaacataggatttcagaacactgctcttggggtctgaatgtttgtcgctcacata