VISDB Viral Integration Site DataBase

VIS ID

TVIS10010527

Fusion event

HBV-KCNT2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1656

Orient

-

Integrated sequence

GTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACA| |TAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT

Chromosome

chr1

Cytoband

q31.3

Reference genome

Start

End

196497541/196528411 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4775 ; hsa-mir-500a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/3391828; hsa-mir-1182/Downstream/54002;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/3406317, chr1-CpG: 24/Downstream/80167

Upstream sequence

CACAGATTGAGAAATGGTCTTTTGATACACTAGTTTTATTATTCTATGTTTTCCTCTGAAAAACAGAAAATTCTATGTTGCCATTTCCATTGAAAAAATA

Downstream sequence

AATTATGTGATTCCTTTCCTCACTTCTCTTAGAATTGTTCGAGCTAGAATCAAGTAGAAATGGCATGAACTAACTTCTTATTTTCCGATGATATCTAAGC