VISDB Viral Integration Site DataBase

VIS ID

TVIS10010528

Fusion event

HBV-KCNT2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

62

Orient

-

Integrated sequence

AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGC| |TGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAG

Chromosome

chr1

Cytoband

q31.3

Reference genome

Start

End

196497584/196528454 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4775 ; hsa-mir-500a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/3391871; hsa-mir-1182/Downstream/53959;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/3406360, chr1-CpG: 24/Downstream/80124

Upstream sequence

CTATGTTTTCCTCTGAAAAACAGAAAATTCTATGTTGCCATTTCCATTGAAAAAATAAATTATGTGATTCCTTTCCTCACTTCTCTTAGAATTGTTCGAG

Downstream sequence

CTAGAATCAAGTAGAAATGGCATGAACTAACTTCTTATTTTCCGATGATATCTAAGCCAAAGAAGGTGTTATTGACTAAACGGCTATTAAGAAATGAAAT