VISDB Viral Integration Site DataBase

VIS ID

TVIS10010533

Fusion event

HBV-SMIM12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2366

Orient

+

Integrated sequence

TCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTC| |CCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGAC

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

35321608/34856007 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-130b-5p ; hsa-mir-96-5p ; hsa-mir-6798-3p ; hsa-mir-2681-5p ; hsa-mir-516b-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-2276-5p ; hsa-mir-518c-5p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-4640-3p ; hsa-mir-4662a-5p ; hsa-mir-6722-5p ; hsa-mir-4755-3p ; hsa-mir-575 ; hsa-mir-4676-5p

Nearest miRNA

hsa-mir-12136/Upstream/186313; hsa-mir-101-1/Downstream/2305556;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/62817, chr1-CpG: 38/Downstream/3574

Upstream sequence

CCACGAAGGCAACAGGGAATGTGACATAAGGAGCATAGGTACGAACCACGGTCCAAAACACAGGCCACATGACATCTGCGGAAAAGCACAAGGCAGCATT

Downstream sequence

AGAGAACCCAGCATCATCTCCCACCAAATAAGAGCAACCCACTAGAGCTCTCCACTTACCAGGCAGCCTGGCACAAtttttttttttttttgagacggag