VISDB Viral Integration Site DataBase

VIS ID

TVIS10010535

Fusion event

HBV-ZMYM4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

664

Orient

-

Integrated sequence

TGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTT| |TCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCC

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

35743502/35277901 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-3149 ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6789-3p ; hsa-mir-4707-3p ; hsa-mir-4258 ; hsa-mir-4438 ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-4698 ; hsa-mir-4705 ; hsa-mir-548au-3p ; hsa-mir-551b-5p ; hsa-mir-7150 ; hsa-mir-8063

Nearest miRNA

hsa-mir-12136/Upstream/608207; hsa-mir-101-1/Downstream/1883662;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/8647, chr1-CpG: 95/Downstream/279178

Upstream sequence

gcccgccctcacaactcccaaaggtgaggtttgggagggagtatcattaggaactcatgagttttaccatatgtgatacattctaatttatcatagtcat

Downstream sequence

tatttttggtgttcaatttgttgtatctttgATGATTGGCGGTCTCTTAAattagtttcctaaggctgccaaaaaactgctacatacttggtagcttaaa