VISDB Viral Integration Site DataBase

VIS ID

TVIS10010539

Fusion event

HBV-PRDX1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2273

Orient

+

Integrated sequence

CTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGT| |GTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGA

Chromosome

chr1

Cytoband

p34.1

Reference genome

Start

End

45976941/45511269 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-7-5p ; hsa-mir-1225-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-23b-3p ; hsa-mir-100-5p ; hsa-mir-510-5p

Nearest miRNA

hsa-mir-12136/Upstream/965717; hsa-mir-101-1/Downstream/5548568;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/10892, chr1-CpG: 64/Downstream/10222

Upstream sequence

GCTGGTCTCTCCACCCCCTGTAGGAAAGGCCTGCCTTGTAAGACACCACAATTCGGCTGAATCTGAAGTCTTGTGTTTTACTAATGGAAAAAAAAAATAC

Downstream sequence

AGAAGAGGTTTTGTTCTCATGGCTGCCCACCGCAGCCTGGCACTAAAACAGCCCAGCGCTCACTTCTGCTTGGAGAAATATTCTTTGCTCTTTTGGACAT