VISDB Viral Integration Site DataBase

VIS ID

TVIS10010541

Fusion event

HBV-GNG12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2973

Orient

+

Integrated sequence

AATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGC| |CAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACA

Chromosome

chr1

Cytoband

p31.3

Reference genome

Start

End

68243177/67777494 (Hg38)

Orient

-

Location type

UTR5

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-423-5p ; hsa-mir-186-5p ; hsa-mir-4279 ; hsa-mir-580-5p ; hsa-mir-584-5p ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-16-1-3p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-144-3p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-5692a ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4477b ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-3973 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4724-5p ; hsa-mir-6816-3p ; hsa-mir-8080 ; hsa-mir-548l ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4775 ; hsa-mir-590-3p ; hsa-mir-153-5p ; hsa-mir-3180-5p ; hsa-mir-6749-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-6756-3p ; hsa-mir-6832-3p ; hsa-mir-3127-3p ; hsa-mir-1182 ; hsa-mir-6814-5p ; hsa-mir-6870-3p ; hsa-mir-3065-5p ; hsa-mir-8063 ; hsa-mir-6504-3p ; hsa-mir-3529-3p ; hsa-mir-216a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1148977; hsa-mir-11399/Downstream/406024;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/90907, chr1-CpG: 89/Downstream/55194

Upstream sequence

GTGTGAATATCATCTCAAAAATAAAGTCAAACAGTCACTTTGTTTAAGAAATGAAGAACTTACCAGTAAGACTTTGTGTGGTCCAATGTTTTCAGGTTTT

Downstream sequence

AAGTGGAATGAATCTGAAATAGAATTAAATAAACATTCCATAAGTAAATCACATTTGGAAAGGGTGTGCTTTCGATCCCAAGTGACTGCCATAACGTTGA