Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010578
Fusion event
HBV-MOB2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1825
Orient
-
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
Start
End
1697307/1676077 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-210/Upstream/419407; hsa-let-7a-2/Downstream/183387;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/23083, chr11-CpG: 21/Downstream/18040
Upstream sequence
ttttctacaagttttagttcccggttttcatgtaaccctctttgtgttaattcttgtggaggacatgagatagggttccaaacttctttctcatgtggct
Downstream sequence
atccagatgtcccagcactatttgtggaaaagactgtctgtcccccgactgagttctgtttgttgcctttgtcaaaaatcaattgacaatctacataaaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.