VISDB Viral Integration Site DataBase

VIS ID

TVIS10010609

Fusion event

HBV-CLSTN3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2838

Orient

+

Integrated sequence

CTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACA| |AGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCC

Chromosome

chr12

Cytoband

p13.31

Reference genome

Start

End

7291600/7139004 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1229-3p ; hsa-mir-877-3p ; hsa-mir-3941 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4457 ; hsa-mir-3922-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-377-3p ; hsa-mir-342-3p

Nearest miRNA

hsa-mir-141/Upstream/174813; hsa-let-7i/Downstream/2100463;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/119952, chr12-CpG: 64/Downstream/50474

Upstream sequence

ATTGAGGGCTGTCTACAAAAGTTTTGCTGTCTGTGGCACTCTTTTAAAGAGACAGTCTGTCATTTGCTGTTTCTTGATTCCCCCCTCACACTGCAAATAT

Downstream sequence

TGGTAATGTTACCCTTGCTATCTTTCTTCAATTCACCCtcatttaatcaaccagtatctattaaatacaactaagtctctgtcattcagctaggttctgg