VISDB Viral Integration Site DataBase

VIS ID

TVIS10010629

Fusion event

HBV-FERMT2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1822

Orient

+

Integrated sequence

GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA

Chromosome

chr14

Cytoband

q22.1

Reference genome

Start

End

53399656/52932938 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-21-5p ; hsa-mir-30b-5p ; hsa-mir-200b-3p ; hsa-mir-218-5p ; hsa-mir-4423-3p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-3166 ; hsa-mir-4299 ; hsa-mir-1324 ; hsa-mir-4728-3p ; hsa-mir-8062 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-8084 ; hsa-mir-138-5p

Nearest miRNA

hsa-mir-208a/Upstream/2632992; hsa-mir-1185-1/Downstream/1015489;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/141037, chr14-CpG: 136/Downstream/17452

Upstream sequence

ATTCTCAACAGTGCAATCTACAACACTATCATCCAGGACCTAACTGAAGTTTTTATAATATGAGTTTCCACAACCATGAAAAACAGGAAAAGAATACCCA

Downstream sequence

ACATATACTTTTGAACTCTGCTGAATCTTATTCTCTCATATAGCGTTATTATTAATCAACAAAATGTAAAACAACAAAGAAATGAACAAAAAAAAACACT