VISDB Viral Integration Site DataBase

VIS ID

TVIS10010636

Fusion event

HBV-GTF2A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2575

Orient

+

Integrated sequence

GGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATC| |AAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATT

Chromosome

chr14

Cytoband

q31.1

Reference genome

Start

End

81658264/81191920 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-96-5p ; hsa-mir-21-5p ; hsa-mir-424-5p ; hsa-mir-3658 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-3653-3p ; hsa-mir-95-5p ; hsa-mir-5697 ; hsa-mir-338-5p ; hsa-mir-6507-5p ; hsa-mir-4422 ; hsa-mir-548e-5p ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-4480 ; hsa-mir-4662a-5p ; hsa-mir-5589-3p ; hsa-mir-517-5p ; hsa-mir-6508-5p ; hsa-mir-8067 ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5680 ; hsa-mir-5684 ; hsa-mir-302f ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-583 ; hsa-mir-106a-3p ; hsa-mir-5002-5p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-1197 ; hsa-mir-1277-5p ; hsa-mir-8080 ; hsa-mir-5692a ; hsa-mir-659-3p ; hsa-mir-4642 ; hsa-mir-6715b-3p ; hsa-mir-92a-1-5p ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-5699-5p ; hsa-mir-4460 ; hsa-mir-4727-3p ; hsa-mir-663b ; hsa-mir-3677-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p

Nearest miRNA

hsa-mir-1260a/Upstream/3925630; hsa-mir-1185-1/Downstream/12756306;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/236703, chr14-CpG: 147/Downstream/28121

Upstream sequence

TAATAAACTATGTTTTCTTCAGAAAAAAAATTACTTAGATAATTTAGAAGAACTTTGTACTAAGAAACAAAAAGACTGCATTTTAGGCTAACGAAGGCAA

Downstream sequence

TTAACAGTGAAAATTGTGGTGGGACAAATAGTTTTTGGAGCCTAGTAACTAAGCTGAAATAGTGAGGAAAACAAAGGCATATTTATATGCTTCTAGAAGA