VISDB Viral Integration Site DataBase

VIS ID

TVIS10010637

Fusion event

HBV-GTF2A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1668

Orient

-

Integrated sequence

CTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCT| |TGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTC

Chromosome

chr14

Cytoband

q31.1

Reference genome

Start

End

81658278/81191934 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-96-5p ; hsa-mir-21-5p ; hsa-mir-424-5p ; hsa-mir-3658 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-3653-3p ; hsa-mir-95-5p ; hsa-mir-5697 ; hsa-mir-338-5p ; hsa-mir-6507-5p ; hsa-mir-4422 ; hsa-mir-548e-5p ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-4480 ; hsa-mir-4662a-5p ; hsa-mir-5589-3p ; hsa-mir-517-5p ; hsa-mir-6508-5p ; hsa-mir-8067 ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5680 ; hsa-mir-5684 ; hsa-mir-302f ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-583 ; hsa-mir-106a-3p ; hsa-mir-5002-5p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-1197 ; hsa-mir-1277-5p ; hsa-mir-8080 ; hsa-mir-5692a ; hsa-mir-659-3p ; hsa-mir-4642 ; hsa-mir-6715b-3p ; hsa-mir-92a-1-5p ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-5699-5p ; hsa-mir-4460 ; hsa-mir-4727-3p ; hsa-mir-663b ; hsa-mir-3677-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p

Nearest miRNA

hsa-mir-1260a/Upstream/3925644; hsa-mir-1185-1/Downstream/12756292;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/236717, chr14-CpG: 147/Downstream/28107

Upstream sequence

TTCTTCAGAAAAAAAATTACTTAGATAATTTAGAAGAACTTTGTACTAAGAAACAAAAAGACTGCATTTTAGGCTAACGAAGGCAATTAACAGTGAAAAT

Downstream sequence

TGTGGTGGGACAAATAGTTTTTGGAGCCTAGTAACTAAGCTGAAATAGTGAGGAAAACAAAGGCATATTTATATGCTTCTAGAAGAACACAGACATTAAG