VISDB Viral Integration Site DataBase

VIS ID

TVIS10010647

Fusion event

HBV-OTUD7A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1822

Orient

+

Integrated sequence

GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA

Chromosome

chr15

Cytoband

q13.3

Reference genome

Start

End

31870470/31578267 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30c-5p ; hsa-mir-491-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-1255b-2-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5582-3p ; hsa-mir-1238-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-153-5p ; hsa-mir-670-3p ; hsa-mir-8080 ; hsa-mir-1197

Nearest miRNA

hsa-mir-1268a/Upstream/513126; hsa-mir-10393/Downstream/2803802;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/93482, chr15-CpG: 177/Downstream/291694

Upstream sequence

tcattatgccctcctcttttttggaatgcaggaaaagctgaccagcatttaacatcCAGCATTTAACATTTAAATATCCACATTTAATATCCAGCATTTA

Downstream sequence

AAAGCTGACCAGCATTTAACATCCACATTTAACATCCAGCATTTAACATCTAATTGGACttaagtctgataagaaacatttaaaatctattctctctgaa