VISDB Viral Integration Site DataBase

VIS ID

TVIS10010654

Fusion event

HBV-SNX1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1633

Orient

-

Integrated sequence

CTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCAC| |CAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACT

Chromosome

chr15

Cytoband

q22.31

Reference genome

Start

End

64394856/64102657 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-95-3p ; hsa-mir-28-3p ; hsa-mir-28-5p ; hsa-mir-571 ; hsa-mir-219a-1-3p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p

Nearest miRNA

hsa-mir-10393/Upstream/231638; hsa-mir-11181/Downstream/659730;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/6228, chr15-CpG: 124/Downstream/48731

Upstream sequence

tcaccattgtaccctctacctccatgagatccatgtttttgactcccacagatgagtgagaacacttgacatttgtctttctgtgcctgacttctttcac

Downstream sequence

ttaacgtaatgacctccagttccatccatgttgctctaaataacaggagttcattcttttttatgcctgaataatagtccattttgtatatataccacgc