VISDB Viral Integration Site DataBase

VIS ID

TVIS10010675

Fusion event

HBV-NFAT5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2936

Orient

+

Integrated sequence

CAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAAT| |CCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCC

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

69737575/69703672 (Hg38)

Orient

-

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-31-5p ; hsa-mir-24-3p ; hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-877-5p ; hsa-mir-652-3p ; hsa-mir-17-5p ; hsa-mir-211-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-4690-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-103a-2-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-580-5p ; hsa-mir-651-3p ; hsa-mir-889-3p ; hsa-mir-1252-5p ; hsa-mir-4476 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6815-3p ; hsa-mir-6826-5p ; hsa-mir-6876-5p ; hsa-mir-3910 ; hsa-mir-548an ; hsa-mir-1468-3p ; hsa-mir-548p ; hsa-mir-921 ; hsa-mir-3174 ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-6507-3p ; hsa-mir-4796-3p ; hsa-mir-374a-5p ; hsa-mir-155-5p ; hsa-mir-7111-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-1827 ; hsa-mir-4419a ; hsa-mir-5681a ; hsa-mir-205-5p ; hsa-mir-4536-5p ; hsa-mir-6770-5p ; hsa-mir-6073 ; hsa-mir-1253 ; hsa-mir-552-3p ; hsa-mir-6768-5p ; hsa-mir-6505-5p ; hsa-mir-6844 ; hsa-mir-9-5p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-613 ; hsa-mir-6124 ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-3202 ; hsa-mir-4756-5p ; hsa-mir-3179 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4797-3p ; hsa-mir-6512-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4261 ; hsa-mir-4496 ; hsa-mir-146a-5p ; hsa-mir-3180-5p ; hsa-mir-345-5p ; hsa-mir-4256 ; hsa-mir-4706 ; hsa-mir-4749-5p ; hsa-mir-4762-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-6731-3p ; hsa-mir-744-5p ; hsa-mir-1273h-5p ; hsa-mir-17-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3689d ; hsa-mir-4311 ; hsa-mir-4443 ; hsa-mir-4487 ; hsa-mir-485-5p ; hsa-mir-490-3p ; hsa-mir-558 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-6884-5p ; hsa-mir-7106-5p ; hsa-mir-7847-3p ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-1225/Upstream/137804; hsa-mir-11401/Downstream/229409;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/136839, chr16-CpG: 19/Downstream/22718

Upstream sequence

AAAAATTCACATATCAGAATAAAAATAAATGTATACTCACTTTATAAAAATCACCACTGCTGTCTTTCCTTAATACTAGCAGTGGAAATGTAAGTGGCTT

Downstream sequence

ACTCTACAAATTTTGGTGCTGGCAAATACATAGGCAAACTGTTGGGAGCTGCTCTAGTTACATTCCTCCCTTCTTATTCCCTTTTTCTCTTCCTCACTTT