Basic Information
VIS ID
TVIS10010677
Fusion event
HBV-LINC02193 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1574
Orient
+
Integrated sequence
CTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCG| |GACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACT
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
90290847/90224439 (Hg38)
End
90290847/90224439 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02193
Nearest miRNA
hsa-mir-11401/Upstream/1508102;
Nearest TSS
ENST00000527434/Upstream/2991;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/52624, None/Downstream
Nearby gene
PRDM7(-148509) ;
Upstream sequence
CTCCTTTAGGATGTCCTTAGAGAATTCATGGAAAAGAAGTTAAATAATTTAAAAGTGCTTTTGGGTACAGCTATTTAGCACTAGAGGGTAAGAGTAGAGA
Downstream sequence
TAGATTGTAAAGATAATAAtagggttaggcataggattaggatctgggtcagagtcagggccggaagtatggttagaggtggggtcatggtcagggtcga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate