VISDB Viral Integration Site DataBase

VIS ID

TVIS10010684

Fusion event

HBV-DDX42 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1481

Orient

-

Integrated sequence

GCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGA| |CTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTG

Chromosome

chr17

Cytoband

q23.3

Reference genome

Start

End

61890471/63813111 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-615-3p ; hsa-mir-345-5p ; hsa-mir-186-5p ; hsa-mir-10a-5p ; hsa-mir-99a-5p ; hsa-mir-6867-3p ; hsa-mir-670-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6734-3p ; hsa-mir-5088-3p ; hsa-mir-6752-3p ; hsa-mir-1324

Nearest miRNA

hsa-mir-10226/Upstream/868799; hsa-mir-1250/Downstream/687663;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/38409, chr17-CpG: 56/Downstream/14255

Upstream sequence

agactccgtctctaaaaaataaaaGTCCCTTACACTAGAAGGCCTAACATCATAGAATCTGTGGTGGTGACTTAACATGCCTGTATCTCAGCTCACCAAA

Downstream sequence

CCCATGCGCTTTGCCTAGATAAAGGAAATGTGGCTTATTAGCACTAGCATTTCTGGTTACTTTGATCTTCTGACTACAGATGAAGAATAAAAGAATTTGG