VISDB Viral Integration Site DataBase

VIS ID

TVIS10010686

Fusion event

HBV-PSMG2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2621

Orient

+

Integrated sequence

CCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAA| |GAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGT

Chromosome

chr18

Cytoband

p11.21

Reference genome

Start

End

12663921/12663922 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-100-5p ; hsa-let-7c-5p ; hsa-mir-570-5p ; hsa-mir-595 ; hsa-mir-1225-5p ; hsa-mir-1229-5p ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-548ba ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-503-3p

Nearest miRNA

hsa-mir-3976/Upstream/1008981; hsa-mir-1-2/Downstream/796025;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/5194, chr18-CpG: 110/Downstream/38263

Upstream sequence

gcagtggtgcgatcatagctcactgcaacctctaactcctgtgctcaaaagaatcctcccagctgggcacagtggtttatgcctgtaatcccagcacttt

Downstream sequence

gggaggttgaggcaggcagatcacctgaggttgggagttcaagaccagcctgaccaacatggagaaaccctgtctctactaaaaatacaaaattagctag