VISDB Viral Integration Site DataBase

VIS ID

TVIS10010688

Fusion event

HBV-CDH2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

640

Orient

+

Integrated sequence

CAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCC| |TATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTAT

Chromosome

chr18

Cytoband

q12.1

Reference genome

Start

End

25623396/28043432 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-204-5p ; hsa-mir-194-5p ; hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-27b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-199a-5p ; hsa-mir-412-3p ; hsa-mir-411-5p ; hsa-mir-216b-3p ; hsa-mir-1244 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-338-3p ; hsa-mir-506-3p ; hsa-mir-153-5p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-587

Nearest miRNA

hsa-mir-1-2/Upstream/1451897; hsa-mir-122/Downstream/2255478;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/857889, chr18-CpG: 257/Downstream/132018

Upstream sequence

aggttacacactgggtacagtgtacactgcttgggtgacaggtacaccaaaatctcagaaatcactactaaagaacttatccatataaccaaaaaccacc

Downstream sequence

tgtaccctaaaaattactgatataaataaatatatatatatatatatatatatatatatataaatatatatatatatatatataaacaggtttgatttga