VISDB Viral Integration Site DataBase

VIS ID

TVIS10010689

Fusion event

HBV-CDH2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1779

Orient

-

Integrated sequence

CAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGG| |AGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGC

Chromosome

chr18

Cytoband

q12.1

Reference genome

Start

End

25623852/28043888 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-204-5p ; hsa-mir-194-5p ; hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-27b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-199a-5p ; hsa-mir-412-3p ; hsa-mir-411-5p ; hsa-mir-216b-3p ; hsa-mir-1244 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-338-3p ; hsa-mir-506-3p ; hsa-mir-153-5p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-587

Nearest miRNA

hsa-mir-1-2/Upstream/1452353; hsa-mir-122/Downstream/2255022;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/858345, chr18-CpG: 257/Downstream/131562

Upstream sequence

GTTGTGTTACAAGTGAATGATCACAGCAGACTGCTTTAGCTGTGAGTGGCCATCCTCAGGCTGGGCCACTCATCTCAGTCTCATCTTTCTCAGAATCTCG

Downstream sequence

GAtttttttttttttttttttttttttttttttttggagacagagtacttctcttgctctgtcactcaggctacagtgcagtggcatgatctcagctcac