ASF1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010697
Fusion event
HBV-ASF1B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1614
Orient
-
Integrated sequence
CCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGA| |GACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAA
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
End
14247071/14136259 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10395/Upstream/62780; hsa-let-7e/Downstream/393284;
Nearest CpG islands
chr19-CpG: 143/Target, None/Upstream, None/Downstream
Upstream sequence
CGTGTTGGCTGGTGGCGGGGGGTCTCCACCGGGAGATCCGGTTGACTGGCGGGCTGGGGGAGATCGGGGTTGGCGGAAGGGGGACGAGGGGTTTCATGGG
Downstream sequence
GGAGATCAAGTTGGCCATGGGAGCGGTTCTCTGAGGGGAGGCCGGGGTCGGCCCGGGGGTGGGGGTCCCCGCACAGGCCCAGCCTCACCGTCCGCCAGGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate