VISDB Viral Integration Site DataBase

VIS ID

TVIS10010705

Fusion event

HBV-LSM14A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2888

Orient

+

Integrated sequence

GAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTC| |TTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGG

Chromosome

chr19

Cytoband

q13.11

Reference genome

Start

End

34699084/34208179 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-320c ; hsa-mir-615-3p ; hsa-mir-15b-5p ; hsa-mir-182-5p ; hsa-mir-196a-5p ; hsa-mir-26a-5p ; hsa-mir-17-5p ; hsa-mir-3941 ; hsa-mir-144-3p ; hsa-mir-373-5p ; hsa-mir-616-5p ; hsa-mir-454-5p ; hsa-mir-1205 ; hsa-mir-371b-5p ; hsa-mir-4474-3p ; hsa-mir-5190 ; hsa-mir-921 ; hsa-mir-3606-5p ; hsa-mir-16-1-3p ; hsa-mir-376c-3p ; hsa-mir-493-5p ; hsa-mir-892a ; hsa-mir-888-3p ; hsa-mir-3136-5p ; hsa-mir-3177-5p ; hsa-mir-4318 ; hsa-mir-4439 ; hsa-mir-4513 ; hsa-mir-4693-5p ; hsa-mir-4699-3p ; hsa-mir-6855-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-548bb-3p ; hsa-mir-943 ; hsa-mir-4684-5p ; hsa-mir-6867-5p ; hsa-mir-6857-3p ; hsa-mir-5571-5p ; hsa-mir-4284 ; hsa-mir-24-3p ; hsa-mir-3182 ; hsa-mir-134-3p ; hsa-mir-7114-5p ; hsa-mir-17-3p ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-1237-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4686 ; hsa-mir-8485 ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-4276 ; hsa-mir-8062 ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p

Nearest miRNA

hsa-mir-10395/Upstream/13808825; hsa-let-7e/Downstream/914521;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/35024, chr19-CpG: 97/Downstream/46134

Upstream sequence

GGTTTTATTAACTGAAgtgaatagtttgaacttttatcttgaggacagtggaagccaccagaaggtctaaagcacgataatgttattacatttatatttt

Downstream sequence

gtaaagaatcactctgactaccatctttaggttggatttagaggttgtggaagggggaggtaCTGTTGAAATATAGTGAAAACCTGCTTAGATGAAATAC