Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010720
Fusion event
HBV-RPL23AP7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2845
Orient
-
Integrated sequence
CTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTA| |CAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGG
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
End
114377555/113619978 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/36882; hsa-mir-10b/Downstream/101312;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/35257, chr2-CpG: 61/Downstream/7034
Upstream sequence
ttccggccccgactctgacccagatcctaatcctatgcctaaccctaTTATTATCTTTACAATCTATCTCTACTCTTACCCTCTAGTGCTAAATAGCTGT
Downstream sequence
ACCCAAAAGCACTTTTAAATTATTTCTTTTCTTGAATTCTCTATGGACATCCTAAAGGAGATGTCAATATGTATTGCATTCCCTCTGAGTGGTATGGCTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.