LRP1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010724
Fusion event
HBV-LRP1B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
487
Orient
+
Integrated sequence
CGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTC| |CAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGA
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
End
141290123/140532554 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-128-1/Upstream/4867076; hsa-mir-10b/Downstream/54072;
Nearest cancer related gene
LRP1B(TSG, No orient, 0)
Upstream sequence
gatgtgatctcaactcactgcaaccttcacctctcgggttcaagcgattctcctgcctcagcatcccgagtagctgggactacaggcgagtgcaaccacg
Downstream sequence
cctggctaatttttgtatttttagtcgagatggggtttcaccatgttgaccaggatggtctcaatctcttgaccttgtgatatgcccacctcagcctccc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate