VISDB Viral Integration Site DataBase

VIS ID

TVIS10010728

Fusion event

HBV-SMC6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1822

Orient

-

Integrated sequence

GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA

Chromosome

chr2

Cytoband

p24.2

Reference genome

Start

End

17874568/17693301 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-222-3p

Nearest miRNA

hsa-mir-3125/Upstream/4955857; hsa-mir-10b/Downstream/1655128;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/152547, chr2-CpG: 131/Downstream/59987

Upstream sequence

tgtatactcaaaggattataaaacatgctgctataaagacacatgcacatgtatgtttattgcggcactattcacaatagcaaagacctggaaccaaccc

Downstream sequence

aaatgtccatcaatgatagactggaaaatgtggcacacatacaccatggaatactatgcagccataaaaaatgacgagttcatgtcctttgtagggacat