VISDB Viral Integration Site DataBase

VIS ID

TVIS10010731

Fusion event

HBV-CPS1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1794

Orient

-

Integrated sequence

ACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAA| |ATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGC

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

211435093/210570369 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-17-5p ; hsa-mir-3121-3p ; hsa-mir-4255 ; hsa-mir-4709-3p ; hsa-mir-7154-5p ; hsa-mir-101-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6744-5p ; hsa-mir-8060 ; hsa-mir-16-1-3p ; hsa-mir-144-3p ; hsa-mir-216a-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-4694-3p ; hsa-mir-6516-5p ; hsa-mir-6738-3p ; hsa-mir-1303 ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-1200 ; hsa-mir-142-3p ; hsa-mir-630 ; hsa-mir-146b-3p ; hsa-mir-6799-3p ; hsa-mir-3173-5p ; hsa-mir-7976 ; hsa-mir-496 ; hsa-mir-302a-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-4682 ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-4778-5p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-10b/Upstream/2815488; hsa-mir-1244-1/Downstream/1855894;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/93557, chr2-CpG: 86/Downstream/1967087

Upstream sequence

AAAAGACATATTGAACACAATCTCAGGGACTATTTCACGCAATAGCAAATGTCTCTTCAACTACAGAGATGGAAAGCAAAATAGAAAACTAGTTTCATGA

Downstream sequence

AGGGAGTGAGAAAAATACCAAACAGAATTGTAGGAATAGGCTCACAAGTGTTGATTTTCTTATGCTAATTTTTACCCTTCTTTAAAATGATCAGAAAGTG